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Hold Shift and use the scroll wheel to scroll horizontally instead of vertically.
Press Ctrl (Windows) or Cmd (Mac) while scrolling to zoom in or out in browsers, Office apps and design tools.
On Windows, holding Alt while scrolling in some applications scrolls line by line rather than page chunks.
Press the Windows key and scroll to zoom the entire desktop if the Magnifier accessibility feature is enabled.
Hold Option and scroll to zoom system-wide when the “zoom with scroll gesture” setting is enabled under Accessibility.
Use Shift + scroll to move sideways across columns in spreadsheets.
Hold Ctrl (or Cmd on Mac) while scrolling to zoom the worksheet in or out.
Hold the Spacebar and drag with the left mouse button to pan around the canvas; hold Alt and scroll to zoom.
Hold the Windows key and scroll to zoom in/out the entire screen using the Magnifier tool.
Use Windows + arrow keys for snapping, while some mice support tilt-wheel or side buttons for window snapping via software.
On mice with extra buttons (e.g., Mac Mouse Fix), assign buttons to open Mission Control, switch Spaces or activate App Exposé.
Use third-party tools like Swish or BetterTouchTool to snap windows into halves or quadrants using swipe gestures.
Middle-click on a tab to close it instantly.
Ctrl (Cmd on Mac) + click the refresh button to duplicate and reload a page in a new tab.
Double-click the edge of a column header (or drag while holding Alt on Windows) to auto-fit the column width.
In Adobe apps, hold Ctrl + Space (Cmd + Space on Mac) and drag to zoom into a selection; hold Alt + Space to zoom out.
Lightweight tool that smooths scrolling and lets you set scroll direction independently for your mouse and trackpad; it uses a special interpolation algorithm and provides per-app settings.
Free utility that reverses scroll direction with independent settings for trackpads and mice and offers step-size control for wheel mice.
Provides butter-smooth scrolling with configurable direction, acceleration and discrete steps; includes drag-to-scroll and per-application settings.
Enhances the scroll wheel so it scrolls the window under the cursor without clicking; supports page-wise scrolling using modifier keys and can reorder windows in the Z-order.
Allows scrolling of the window under the mouse even when it doesn’t have focus; can enable scroll wheel support in old applications and reverse scroll direction.
Small utility that lets you scroll any window under the pointer even if it’s not in the foreground, provides horizontal scrolling, Alt+mouse operations for moving/resizing windows and optional volume control via the wheel.
Comprehensive customization tool for macOS that lets you create custom gestures and shortcuts for trackpads, mice and keyboards; includes window snapping, clipboard management and automation features.
Advanced driver allowing you to assign additional functions to mouse buttons such as double-clicks, modifier clicks and application switching, and adjust cursor sensitivity beyond Apple’s options.
Replicates trackpad-like gestures using mouse buttons: look up words or open Mission Control with button 4; move between desktops, trigger App Exposé or show desktop with button 5; offers smooth 360° scrolling and independent scroll direction.
Remaps mouse buttons and scroll wheel actions, creates application-specific profiles, supports simulated keystrokes, button chording, timed actions and customized scrolling for up to five-button mice.
Powerful scripting tool that lets you define macros and remap keys or mouse inputs using an easy scripting language or a macro recorder; can trigger complex actions with a single button press.
Gesture-driven window manager providing thirty window, dock and menubar gestures. It lets you snap windows into halves or quadrants with directional swipes and control apps with intuitive gestures.
Beyond remapping, it adds advanced gestures and window management: assign swipe gestures to snap windows to different positions, trigger actions like Mission Control or Launchpad, and manage spaces.
Adds trackpad-like gestures via mouse buttons: use button 4 for dictionary lookup or Mission Control, button 5 to switch desktops or activate App Exposé, plus smooth scroll and customizable scroll direction.
Also useful for window management: in addition to scrolling inactive windows, it lets you use Alt + mouse to move or resize windows and supports horizontal scrolling.
Its advanced features include button chording and timed actions that can be used for custom window management gestures and macros.